ADRIAMYCIN-PFS

Drug Name: ADRIAMYCIN-PFS

ADRIAMYCIN-PFS DESCRIPTION:
DOXORUBICIN - INJECTION (dox-oh-REW-beh-sin)

COMMON ADRIAMYCIN-PFS BRAND NAME(S):
Adriamycin, Rubex

ADRIAMYCIN-PFS SIDE EFFECTS:
Nausea, vomiting and diarrhea are common side effects. Taking the medication on an empty stomach may help relieve vomiting. Changes in diet such as eating several small meals or limiting activity may help lessen some of these effects. In some cases, drug therapy may be necessary to prevent or relieve nausea and vomiting. ADRIAMYCIN-PFS may turn your urine a reddish color. This is a normal effect of the drug as it leaves your body and is not blood in the urine. The effect should clear up within 2 days after each dose is given. Temporary hair loss is another common side effect; normal hair growth should return after treatment has ended. Contact your doctor immediately if you experience any of the following symptoms: sores in mouth or on lips, fever or chills, cough or hoarseness, lower back or side pain, painful or difficult urination, fast or irregular heartbeat, shortness of breath, wheezing, swelling of feet or lower legs, stomach pain, joint pain, unusual bleeding or bruising, black or tarry stools, blood in urine or stools, small red spots on the skin, skin rash, itchy skin. If you notice other effects not listed above, contact your doctor or pharmacist.

HOW TO USE ADRIAMYCIN-PFS:
ADRIAMYCIN-PFS: This is a potent medication. Use it exactly as prescribed. Tell your doctor or nurse immediately if you experience pain, burning or redness at the place where injected. Unless your doctor instructs you otherwise, drink plenty of fluids while taking ADRIAMYCIN-PFS. This helps your kidneys to remove the drug from your body and avoid some of the side effects. Do not stop taking ADRIAMYCIN-PFS, even if you feel nauseated or experience vomiting.

ADRIAMYCIN-PFS WARNING:
ADRIAMYCIN-PFS must be given slowly and directly into a vein (IV) through other intravenous (IV) fluids. Do not inject ADRIAMYCIN-PFS into the muscle (IM) or just beneath the skin (subcutaneously). If ADRIAMYCIN-PFS accidentally leaks into surrounding tissue, the skin and/or muscle may be severely damaged. Notify the doctor immediately if redness, pain, or swelling occur at (or around) the injection site. Doxorubicin may cause heart problems (including heart failure) or bone marrow suppression. Notify your doctor immediately if you develop an irregular heartbeat, trouble breathing, swelling of the hands or feet, easy bruising or bleeding, dry cough, or signs of infection such as fever, unusual fatigue, or persistent sore throat. Heart problems may occur during therapy or sometimes, months to years after receiving ADRIAMYCIN-PFS. The risk of developing heart problems varies depending on your dose and condition. Tell your doctor if you have liver problems since the dose should be decreased in this situation. Your doctor will closely monitor you while you are using this medication.

ADRIAMYCIN-PFS USES:
Doxorubicin is one of a large group of drugs known as "antineoplastics"; these drugs are also known as cancer drugs, chemotherapy, or "chemo". They are used in the treatment of various cancers to slow or stop the growth of cancer cells. A combination of different types of cancer drugs will often be used to achieve better results and minimize side effects.

ADRIAMYCIN-PFS PRECAUTIONS:
Tell your doctor if you have: blood disorders, heart disease, liver disease. ADRIAMYCIN-PFS is not recommended for use during pregnancy. Consult your doctor before using ADRIAMYCIN-PFS. It is not known if ADRIAMYCIN-PFS is excreted into breast milk. Consult your doctor before breast-feeding. Because ADRIAMYCIN-PFS can affect the production of sperm in men, a reliable form of birth control is recommended while using ADRIAMYCIN-PFS.

ADRIAMYCIN-PFS DRUG INTERACTIONS:
Tell your doctor of all nonprescription and prescription medication you may use, especially of: digoxin, other anti-cancer drugs, progesterones, verapamil, cyclosporine, phenytoin, phenobarbital, streptozocin, live virus vaccines. Do not start or stop any medicine without doctor or pharmacist approval.

ADRIAMYCIN-PFS OVERDOSE:
If overdose is suspected, contact your local poison control center or emergency room immediately.

ADRIAMYCIN-PFS NOTES:
ADRIAMYCIN-PFS can lower your body's ability to fight an infection. Notify your doctor if you develop any signs of an infection such as fever, sore throat, rash, or chills. Avoid touching your eyes or inside your nose without first washing your hands. Use caution with sharp objects like safety razors or nail cutters and avoid activities such as contact sports in order to lower the chance of getting cut, bruised or injured. Do not have immunizations/vaccinations without consent of your doctor, and avoid contact with people who have recently received oral polio vaccine. Regular doctor visits are important. Frequent blood tests will be done to monitor therapy.

MISSED ADRIAMYCIN-PFS DOSE:
For optimal benefits, it is important to receive each scheduled dose of ADRIAMYCIN-PFS as directed. If you miss a dose, inform your doctor.

ADRIAMYCIN-PFS STORAGE:
Store powder at room temperature. Your condition can cause complications in a medical emergency. For information on enrollment call Medic Alert(TM) at 1-800-854-1166. In Canada call 1-800-668-1507.