DARAPRIM

Drug Name: DARAPRIM

DARAPRIM DESCRIPTION:
PYRIMETHAMINE - ORAL (pir-ih-METH-uh-meen)

COMMON DARAPRIM BRAND NAME(S):
Daraprim

DARAPRIM SIDE EFFECTS:
Nausea, stomach upset or loss of appetite may occur especially the first several days as your body adjusts to the medication. Other effects reported include headache, lightheadedness, dry mouth, diarrhea, trouble sleeping. If any of these effects continue or become bothersome, inform your doctor. Notify your doctor if you develop a skin rash, sore throat, unusual bruising, pale skin, swelling of the tongue, depression, irregular heartbeat. Use caution driving or operating machinery if DARAPRIM makes you lightheaded. DARAPRIM may cause blood disorders. It is important that lab tests be done periodically while taking DARAPRIM to monitor for this. If you notice other effects not listed above, contact your doctor or pharmacist.

HOW TO USE DARAPRIM:
DARAPRIM: Take DARAPRIM by mouth with food or meals as directed. For preventing malaria, this is usually taken once a week. For treatment of a malarial attack, this is taken once a day for 2 days, then given once a week. In the treatment of toxoplasmosis, this may be given once or twice a day for up to 5 weeks. Take DARAPRIM for the full time prescribed. Stopping therapy too soon may result in ineffective treatment.

DARAPRIM USES:
DARAPRIM is used in the treatment and prevention of malaria or the treatment of toxoplasmosis (a parasitic infection). Pyrmethamine is often taken in combination with other antimalaria medication.

DARAPRIM PRECAUTIONS:
Tell your doctor if you have any: pre-existing kidney disease, liver disease, blood disorders, allergies. DARAPRIM should be used only if clearly needed during pregnancy. Discuss the risks and benefits with your doctor. DARAPRIM appears in breast milk. Consult your doctor before breast-feeding.

DARAPRIM DRUG INTERACTIONS:
Tell your doctor of any over-the-counter or prescription medication you may take including: sulfa antibiotics, phenytoin, methotrexate. Do not start or stop any medicine without doctor or pharmacist approval.

DARAPRIM OVERDOSE:
If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include vomiting, temporary stop in breathing, fever, fast heartbeat, and seizures.

DARAPRIM NOTES:
Laboratory tests will be done periodically while taking DARAPRIM to monitor its effects.

MISSED DARAPRIM DOSE:
If you miss a dose, take it as soon as remembered; do not take it if it is near the time for the next dose, instead, skip the missed dose and resume your usual dosing schedule. Do not "double-up" the dose to catch up.

DARAPRIM STORAGE:
Store at room temperature between 59 and 86 degrees F (15 to 30 degrees C) away from heat and light. Do not store in the bathroom.