MARPLAN

Drug Name: MARPLAN

MARPLAN DESCRIPTION:
MAO INHIBITORS - ORAL

COMMON MARPLAN BRAND NAME(S):
Nardil, Parnate

MARPLAN SIDE EFFECTS:
May cause drowsiness, dizziness, increased sun sensitivity or blurred vision. Use caution performing tasks that require alertness. May initially cause dizziness and lightheadedness when rising too quickly from a sitting or lying position. Other side effects include stomach upset, loss of appetite, tremors, irritability, sleeplessness, or flushing. These effects should subside as your body adjusts to the medication. Notify your doctor promptly if the following effects occur: severe headache, rapid or irregular heart rate, skin rash, fever, yellowing of the eyes or skin. If you notice other effects not listed above, contact your doctor or pharmacist.

HOW TO USE MARPLAN:
MARPLAN: May be taken with food if stomach upset occurs. Take this exactly as prescribed. Try to take each dose at the same time(s) each day so you remember to routinely take it. It may take a few weeks for the full benefits of this medication to be noticed. Do not stop taking MARPLAN without first consulting your doctor.

MARPLAN USES:
MARPLAN is used to treat depression.

MARPLAN PRECAUTIONS:
Before using MARPLAN, tell your doctor your medical history, especially of: heart or circulation problems, liver or kidney disease, head trauma, pheochromocytoma (specific type of tumor), alcohol use, mental/emotional conditions, frequent or severe headaches, high blood pressure, any allergies. MARPLAN should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. MARPLAN may be excreted into breast milk and pose a risk to a nursing infant. Consult your doctor before breast-feeding.

MARPLAN DRUG INTERACTIONS:
Be sure to tell your doctor what medicines (both prescription and nonprescription) you are taking, including: meperidine and other narcotic pain relievers; drugs used for depression especially SSRI's (e.g., fluoxetine, paroxetine) and tricyclic antidepressants (e.g., amitriptyline, doxepin); other MAO inhibitors (e.g., furazolidone, linezolid, selegiline); dextromethorphan (an ingredient found in cough syrups); sumatriptan; bethanidine; indoramin; buspirone; levodopa; certain sympathomimetics found in over-the-counter cold remedies and asthma inhalers (e.g., epinephrine, pseudoephedrine, phenylephrine); dexfenfluramine; fenfluramine; insulin and oral antidiabetic drugs; sedatives and drugs used to aid sleep; blood pressure medications. Consult your doctor about the need to watch your intake of foods containing tyramine. It is possible consuming tyramine- containing foods while using MARPLAN could cause headache and/or increased blood pressure and could lead to a medical emergency. Tyramine food precautions should be observed for at least 2 weeks after you stop using MARPLAN. The following is a partial list of tyramine-containing foods: Meat or Fish - pickled herring/liver/dry sausage/salami/meats prepared with tenderizer; Dairy - yogurt/sour cream/aged cheeses (cream or cottage cheese are okay); Beverages - beer/red wine/sherry - Avoid excessive amount of caffeine-containing colas/coffee/tea; Fruits and Vegetables - avocado/bananas/figs/raisins/broad beans/sauerkraut; Other - yeast extract/soy sauce/large amounts of chocolate. Do not start or stop any medicine without doctor or pharmacist approval.

MARPLAN OVERDOSE:
If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include convulsions, cool or clammy skin, severe dizziness or headache, hallucinations, drowsiness, slow or shallow breathing, fainting, irritability, sleeplessness, anxiety, weakness, sweating, confusion, unconsciousness, unusual fast heartbeat, or chest pain.

MARPLAN NOTES:
Do not share MARPLAN with others.

MISSED MARPLAN DOSE:
If you miss a dose, take as soon as remembered unless the next scheduled dose is within 2 hours. If so, skip the missed dose and resume your usual dosing schedule. Do not "double-up" the dose to catch up.

MARPLAN STORAGE:
Store at room temperature away from moisture and sunlight. Do not store in the bathroom. Your condition can cause complications in a medical emergency. For information on enrollment call Medic Alert(TM) at 1-800-854-1166. In Canada call 1-800-668-1507.