NYDRAZID

Drug Name: NYDRAZID

NYDRAZID DESCRIPTION:
ISONIAZID - INJECTION (eye-so-NYE-uh-zid)

COMMON NYDRAZID BRAND NAME(S):
Nydrazid

NYDRAZID SIDE EFFECTS:
May cause stomach upset, heartburn, nausea or dizziness. These effects should disappear as your body adjusts to the medication. If these effects persist or worsen, notify your doctor. Notify your doctor if you experience blurred vision, darkening of the urine, skin rash, yellowing of the eyes or skin or numbness or tingling of the hands or feet. In the unlikely event you have an allergic reaction to this drug, seek immediate medical attention. Symptoms of an allergic reaction include rash, itching, swelling, dizziness or trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist.

HOW TO USE NYDRAZID:
NYDRAZID: NYDRAZID is injected into a muscle (IM) once daily or use as directed by your doctor. Do not stop using NYDRAZID without your doctor's approval. Stopping therapy too early may result in a relapse of the infection. Vitamin B6 (pyridoxine) may be prescribed to prevent numbness and tingling (neuropathy).

NYDRAZID WARNING:
NYDRAZID has caused severe, even fatal, liver problems (e.g., hepatitis). Liver problems increase with age and with daily use of alcohol. Hepatitis can develop with use of this drug at any time during treatment. Stop using NYDRAZID and notify your doctor immediately if you develop unusual fatigue, weakness, loss of appetite, nausea, vomiting, dark urine, yellowing of the eyes or skin, or stomach or abdominal pain. Your doctor may decide to slowly restart isoniazid after these symptoms disappear and lab tests return to normal. People with active (acute) liver problems should not use this medication for preventative treatment until after the liver problems have stopped. Your doctor will monitor your liver function tests at least every month to discuss your progress.

NYDRAZID USES:
NYDRAZID is used to prevent and treat tuberculosis.

NYDRAZID PRECAUTIONS:
Tell your doctor your medical history, especially of kidney or liver problems, diabetes, a history of alcohol use, if you have previously been treated for tuberculosis and of any allergies you may have. Alcohol can reduce the effectiveness of isoniazid and increase side effects. Minimize alcohol consumption. NYDRAZID should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. Isoniazid is excreted into breast milk. Consult your doctor before breast-feeding.

NYDRAZID DRUG INTERACTIONS:
Tell your doctor of all medications you may use (both prescription and nonprescription) especially of antacids that contain aluminum and also of disulfiram, phenytoin, rifampin and carbamazepine. NYDRAZID may interfere with the effectiveness of birth control pills. Discuss using other methods of birth control with your doctor. Isoniazid can cause false positive results in diabetics using Clinitest to test their urine. Consult your doctor or pharmacist for recommendations. Do not start or stop any medicine without doctor or pharmacist approval.

NYDRAZID OVERDOSE:
If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include nausea; vomiting; dizziness; slurring of speech; blurred vision; numbness, tingling, or burning of your arms, hands, legs, or feet; joint pain; hallucinations; and loss of consciousness.

NYDRAZID NOTES:
Periodic eye tests may be done while you are taking this medication.

MISSED NYDRAZID DOSE:
If you miss a dose, use it as soon as remembered; do not use if it is almost time for the next dose. Instead, skip the missed dose and resume your usual dosing schedule. Do not "double-up" the dose to catch up.

NYDRAZID STORAGE:
Store at room temperature away from moisture and sunlight.