PROPULSID

Drug Name: PROPULSID

PROPULSID DESCRIPTION:
CISAPRIDE - ORAL (SIS-uh-pride)

COMMON PROPULSID BRAND NAME(S):
Propulsid

PROPULSID SIDE EFFECTS:
Diarrhea, nausea, headache, stuffy nose, constipation or coughing may occur infrequently as your body adjusts to the medication. If any of these effects persist or worsen, inform your doctor promptly. Notify your doctor if you develop vision changes, chest pain, mental/mood changes or stomach pain while taking PROPULSID. PROPULSID can rarely cause irregular heartbeat and dizziness/fainting. If these effects occur, stop taking your drug and contact your doctor immediately. In the unlikely event you have an allergic reaction to this drug, seek immediate medical attention. Symptoms of an allergic reaction include rash, itching, swelling, dizziness or trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist.

HOW TO USE PROPULSID:
PROPULSID: PROPULSID is taken by mouth at least 15 minutes before meals and at bedtime. Take this as directed. Do not increase your dose, take this more often than prescribed or stop taking this without first consulting your doctor. LIQUID SUSPENSION FORM: Shake the bottle well before each use.

PROPULSID WARNING:
Serious, even fatal heart problems have occurred when cisapride was used alone or with other drugs such as azole antifungals (e.g., ketoconazole), macrolide antibiotics (e.g., erythromycin), nefazodone, protease inhibitors (e.g., ritonavir); drugs used to treat irregular heartbeats such as quinidine or sotalol; antidepressants (e.g., tricyclic or certain tetracyclics), antipsychotics (e.g., certain phenothiazines, sertindole), astemizole, sparfloxacin, and terodiline. This is not a complete list of drugs that should not be used with cisapride. Tell your doctor of all medications you are using. Do not use cisapride if you have (or have had) heart problems, kidney problems, chest pain (angina), low potassium or magnesium levels, or breathing problems. Use only the amount prescribed by your doctor.

PROPULSID USES:
PROPULSID is used to treat symptoms of nighttime heartburn due to reflux disease.

PROPULSID PRECAUTIONS:
Tell your doctor if you have any pre-existing intestinal disorders, bleeding ulcers; lung, kidney or liver disease; heart problems (e.g., QT prolongation); cancer; certain blood disorders (electrolyte disorders such as hypokalemia, hypocalcemia, hypomagnesemia) that may be caused by sudden loss of water, vomiting, or poor diet; eating disorders (e.g., anorexia or bulemia); or any allergies. Limit alcohol intake as it may aggravate drug side effects. Caution is advised when using PROPULSID in children less than 16 years of age because they may be more sensitive to the effects of the drug. PROPULSID should be used only if clearly needed during pregnancy. Discuss the risks and benefits with your doctor. Since small amounts of PROPULSID are found in breast milk, consult your doctor before breast-feeding.

PROPULSID DRUG INTERACTIONS:
Tell your doctor of all the prescription and nonprescription drugs you use, especially "blood thinners" such as warfarin, anticholinergics such as dicyclomine, anti-anxiety drugs, tranquilizers, sedatives, "azole antifungals" (e.g., ketoconazole, fluconazole), troleandomycin, erythromycin, clarithromycin; drugs affecting the heart (QT prolongation) such as quinidine, procainamide, sotalol, terfenadine, astemizole, tricyclic antidepressants (e.g., amitriptyline), bepridil, certain quinolone antibiotics (e.g., sparfloxacin, grepafloxacin), certain antipsychotics (e.g., chlorpromazine, prochlorperazine, sertindole), pentamidine, pimozide, promethazine, halofantrine, amiodarone; certain protease inhibitors (e.g., ritonavir, indinavir); nefazodone, cimetidine, mibefradil, terodiline, certain diuretics/"water pills" (e.g., furosemide), fluvoxamine, or certain tetracyclic antidepressants (e.g., maprotiline). Do not eat grapefruit or drink grapefruit juice unless your doctor instructs you otherwise. Do not start or stop any medicine without doctor or pharmacist approval.

PROPULSID OVERDOSE:
If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include diarrhea, stomach cramping, trouble sleeping, seizures, or irregular heartbeat.

PROPULSID NOTES:
Talk to your health care provider about dietary changes and raising the head of your bed which may help relieve heartburn. Certain tests (such as EKG and electrolytes) may be done as part of drug monitoring before and during therapy.

MISSED PROPULSID DOSE:
If you miss a dose, take it as soon as remembered; do not take it if it is near the time for the next dose, instead, skip the missed dose and resume your usual dosing schedule. Do not "double-up" the dose to catch up.

PROPULSID STORAGE:
Store at room temperature between 59 and 86 degrees F (15 to 30 degrees C) away from heat and light. Do not store in the bathroom.