RESCRIPTOR

Drug Name: RESCRIPTOR

RESCRIPTOR DESCRIPTION:
DELAVIRDINE - ORAL (deh-LAV-er-deen)

COMMON RESCRIPTOR BRAND NAME(S):
Rescriptor

RESCRIPTOR SIDE EFFECTS:
Headache or nausea might occur. If these persist or worsen, notify your doctor. Report to your doctor promptly: rash, itching. Unlikely but report promptly: vomiting, stomach pain: yellowing skin or eyes; fever, trouble breathing, swelling, dizziness/fainting, persistent sore throat; unusual bleeding or bruising. If you notice other effects not listed above, contact your doctor or pharmacist.

HOW TO USE RESCRIPTOR:
RESCRIPTOR: Take by mouth exactly as directed, usually three times a day with or without food. For ease of use, the tablets may be dissolved in water before swallowing. To dissolve the drug, add the tablets for the next dose to at least 3 ounces (90 cc) of water, allow to stand for a few minutes, and then stir. The liquid should be consumed promptly. The glass should be rinsed and the rinse swallowed to be sure the whole dose of medicine is taken. If taking didanosine or antacids, take them one hour apart from RESCRIPTOR. For anyone with lack of stomach acid (achlorhydria), take this drug with an acidic beverage (e.g., orange or cranberry juice).

RESCRIPTOR WARNING:
Didanosine-delavirdine combination treatment is not recommended because delavirdine did not add to the benefit of didanosine in a clinical test. The HIV virus quickly develops resistance when delavirdine is used alone. Therefore, delavirdine must always be used with other proven combinations of anti-HIV medications.

RESCRIPTOR USES:
RESCRIPTOR is used in the treatment of infection with HIV (the virus that causes AIDS). It is used in combination with other HIV medications (antiretrovirals) in selected patients. No cure exists for HIV infection, and the illnesses associated with your disease (infections, etc.) may continue.

RESCRIPTOR PRECAUTIONS:
Before taking RESCRIPTOR, tell your doctor your entire medical history, including: allergies (particularly drug allergies), liver disease, Report promptly to your doctor: severe rash, rash with symptoms (e.g., fever, blistering, mouth sores, swelling, muscle/joint aches). RESCRIPTOR should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. It is not known whether RESCRIPTOR is excreted into human milk. Avoid breast-feeding to prevent transmission of HIV infection to an uninfected infant. Caution is advised when using RESCRIPTOR in children under 16 years of age.

RESCRIPTOR DRUG INTERACTIONS:
Tell your doctor of all nonprescription and prescription medication you may take, especially: antacids (containing aluminum and magnesium), clarithromycin, fluoxetine, ketoconazole, phenytoin, phenobarbital, carbamazepine, rifabutin, rifampin, terfenadine, astemizole, dapsone, ergot derivatives (e.g., cafergot, ergotamine), alprazolam, midazolam, triazolam, nifedipine-like calcium channel blockers, cisapride, quinidine, warfarin, amphetamines, H2 blockers (e.g., cimetidine), St John's wort, sildenafil, protease inhibitors (e.g., amprenavir). Do not start or stop any medicine without doctor or pharmacist approval.

RESCRIPTOR OVERDOSE:
If overdose is suspected, contact your local poison control center or emergency room immediately.

RESCRIPTOR NOTES:
Do not share RESCRIPTOR with anyone else. This medication has not been shown to reduce the chance of transmitting HIV to others.

MISSED RESCRIPTOR DOSE:
If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not "double-up" the dose to catch up.

RESCRIPTOR STORAGE:
Store at room temperature between 68 and 77 degrees F (20-25 degrees C) away from light and moisture. Keep container tightly closed. Your condition can cause complications in a medical emergency. For information on enrollment call Medic Alert(TM) at 1-800-854-1166. In Canada call 1-800-668-1507.